Work experience (More than 10 years in academic teaching and quality assurance requirements): June 2024 till now: Professor in Microbiology and Immunology department, Faculty of pharmacy, Ahram Canadian University (ACU) - Head of microbiology and immunology department. August 2023 till June 2024: Acting head of microbiology and immunology department- Member in the education and student affairs committee. Member in the committee of post graduate studies. 2022-2023: Coordinator for Bachelor of pharmacy-Pharm D program and head of control (level 4). 2021 till now: Member in technical support team in quality assurance center and member in preparing and following up the strategic plan for ACU. 2020 till 2022: Head of Quality assurance unit, Faculty of pharmacy, ACU. My research interests include various research fields such as: - Cell culture technology and its applications - Virology and the use of new stabilizers and adjuvants in improving the production of viral vaccines - Environmental biotechnology via the application of the microbial enzymes in the biodegradation of toxic environmental pollutants - Novel antibacterial, antiviral and anticancer agents and their mechanisms of action - Biological applications of nanoparticles and liposomes - Factors affecting microbial virulence, biofilm formation and resistance to antibiotics - Viral vaccines development for enhancing their immune response - Phage therapy as a novel alternative to antibiotics
♦ PhD degree in Microbiology and Immunology, Faculty of Pharmacy. Cairo University (2013). ♦ Master’s degree in Microbiology and Immunology, Faculty of Pharmacy. Cairo University (2009). ♦ Bachelor of Pharmaceutical Sciences, Faculty of Pharmacy. Cairo University. (May 2001)
♦ Shebl RI, Ali A E, Mohamed A F and Amin. M A. (2009). Biological behavior of Varicella Zoster Virus recovered from Egyptian children in cell culture as a useful tool for antiviral screening assays. Egyptian Journal of Biotechnology. 32: 465-480. ♦ Shebl RI, Amin MA, Emad-Eldin A, Bin Dajem SM, Mostafa AS, Ibrahim EH, Mohamed AF. (2012). Antiviral activity of liquorice powder extract against varicella zoster virus isolated from Egyptian patients. Chang Gung Med J. 2012 May 1;35(3):231-9. ♦ Shebl RI, Ali A E, Mohamed A F and Amin. M A. (2012). Cerastes cerastes and Vipera lebetina snake venoms apoptotic – stimulating activity to human breast cancer cells and related gene modulation. Journal of Cancer science and therapy. 4(10):317-323. ♦ Shebl RI, Ali A E, Mohamed A F and Amin. M A. (2012). Antimicrobial Profile of Selected Snake Venoms and Their Associated Enzymatic Activities. British Microbiology Research Journal. 2(4): 251-263. ♦ Alyan M S, Shalaby M A, El-Sanousi A A, Fahmy A, El-Sayed M, Shebl RI. (2016). New trends in cancer therapy and antiviral drug research. International journal of advanced research.4 (5):698-710. ♦ Al-Olayan EM, Mohamed AF, El-Khadraqy MF, Shebl RI, Yehia H. (2016). An Alternative Inactivant for Rift Valley Fever Virus using Cobra Venom-derived L-Amino Oxidase, which is Related to its Immune Potential. Brazilian Archives of Biology and Technology.59:1-12. ♦ Yaseen RA, Mohamed AF, Bakkar A, Shebl RI, Sabatseir JM. (2016). Grape Seed Extract Induces G2/M Cell Cycle Arrest and Apoptosis Via Generation of Reactive Oxygen Species in Breast and Colon Cancer Cell lines. Inventi Rapid: Animal Models &Cell Assays, 2017(1):1-6. ♦ Ayman M, Mohamed AF, Bakkar A, Shebl RI, Sabatier J-M. (2017). The Bacillus Calmette-Guérin Derived Purified Protein (PPD) Potentiates In-Vitro Anti-cancer Activity of Cerastes cerastes Snake Venom in Colon and Prostate Cancer Cells. Inventi Rapid: Molecular Pharmacology. 2017(2):1-9. ♦ Shebl RI, Farouk F, Azzazy HM. (2017). Effect of Surface charge and hydrophobicity modulation on the antibacterial and antibiofilm potential of magnetic iron nanoparticles. Journal of Nanomaterials. 2017. Article ID 3528295, 15 pages https://doi.org/10.1155/2017/3528295. ♦ Ayman M, El-Aziz Badr DA, Shebl RI, Mohamed AF. (2017). Comparative Evaluation of Alum and MPL as Adjuvants Toxicity and Related Immune Potential of Adjuvanted Rabies Vaccine. SL Gastroenterol. 1(1):112. ♦ Elhusseiny S M, Amin H M. and Shebl R I. (2017). Mathematical Model for Optimization of Naphthalene Degradation by Pleurotus ostreatus. New Egyptian journal of Biotechnology. Vol. 55. ♦ Shebl RI. Anti-cancer potential of captopril and botulinum toxin type-a and associated p53 gene apoptotic stimulating activity. Iranian journal of pharmaceutical research: IJPR. 2019;18(4):1967. ♦ Mahmoud MH, Amin MA, Shebl RI, Mohamed AF, Zafer MM. (2018). Influence of Subminimal Inhibitory Concentrations of Some Bioactive Compounds on the Biofilm Formation Ability and Virulence Factors of Multiple Drug Resistant Acinetobacter baumannii Clinical Isolates. African Journal of Microbiology Research. 28;12(12):275-83. ♦ Elhusseiny SM, Amin HM, Shebl RI. (2018). Modulation of Laccase Transcriptome During Biodegradation of Naphthalene by White Rot Fungus Pleurotus ostreatus. International Microbiology. 2018:1-9. ♦ Farouk F and Shebl RI. (2018). Comparing surface modifications of Zinc Oxide Nanoparticles for modulation of their antiviral activity against Herpes Simplex Virus Type-1. International Journal of Nanoparticles and Nanotechnology. 4:021. ♦ Ebtesam M. Al-Olayan, Manal F. El-Khadragy, Aly Fahmy, Amany Khalil Mohamed, Rania Ibrahim Shebl and Hany Yehia. (2019). Evaluation of different stabilizers and inactivating compounds for the enhancement of Vero cell rabies vaccine stability and immunogenicity: In vitro study. Biomed Research International. Volume 2019, Article ID 4518163, 9 pages. ♦ Shebl RI and Mosaad Y O. (2019). Frequency and Antimicrobial Resistance Pattern among Bacterial Clinical Isolates Recovered from Different Specimens in Egypt. Central African Journal of Public Health. 5 (1): 36-45. doi: 10.11648/j.cajph.20190501.16. ♦ Adel-El-bialy AM, Abuamara TM, Amer ME, Shbel RI, Matar ER, Abulghait M, Mohamed AF. Histopathological, Biochemical and Genetic Profile Post Application of Free Silver Nanoparticles and H2O2 Combined Form in Vitro Study. J Cytol Histol 12 (2021): 564. ♦ Mohamed AF, Abuamara TM, Amer ME, Ei-Moselhy LE, Gomah TA, Matar ER, Shebl RI, Desouky SE, Abu-Elghait M. Genetic and Histopathological Alterations in Caco-2 and HuH-7 Cells Treated with Secondary Metabolites of Marine fungi. Journal of Gastrointestinal Cancer. 2021 May 11;52(2):1-6. ♦ Shebl RI, Amer ME, Abuamara TM, Matar ER, Ahmed HF, Gomah TA, El Moselhy LE, Abu-Elghait M, Mohamed AF. Staphylococcus aureus derived hyaluronic acid and bacillus Calmette-Guérin purified proteins as immune enhancers to rabies vaccine and related immuno-histopathological alterations. Clinical and Experimental Vaccine Research. 2021 Sep 1;10(3):229-39. DOI: 10.7774/cevr.2021.10.3.229 ♦ Yehia HM, Elkhadragy MF, Shebl RI, Al-Masoud AH, El-Din MF. Control some foodborne pathogens, contaminated bacteria and fungi by fabrication calyx cape gooseberry (Physalis peruviana L.) nanoparticles. Food Science and Technology. 2022 Jan 7;42:e116021. ♦ Mohamed AF, Nasr M, Amer ME, Abuamara TM, Abd-Elhay WM, Kaabo HF, Matar EE, El Moselhy LE, Gomah TA, Deban MA, Shebl RI. Anticancer and antibacterial potentials induced post short-term exposure to electromagnetic field and silver nanoparticles and related pathological and genetic alterations: in vitro study. Infectious Agents and Cancer. 2022 Feb;17(1):1-6. DOI: 10.1186/s13027-022-00416-4 ♦ Elhabak M, Shebl RI, Omar S. Modulating liposomal nanoparticles to enhance uptake and targeting of methicillin-resistant Staphylococcus aureus. Future Microbiol. 2023 Apr;18:343-355. DOI: 10.2217/fmb-2022-0069 ♦ Badawy MS, Elkhatib WF, Shebl RI. Mathematical pharmacodynamic modeling for antimicrobial assessment of ceftazidime/colistin versus gentamicin/meropenem combinations against carbapenem-resistant Pseudomonas aeruginosa biofilm. Annals of Clinical Microbiology and Antimicrobials. 2023 Dec;22(1):1-1. DOI: 10.1186/s12941-023-00597-9 ♦ Shebl RI, Elkhatib WF, Badawy MS. Modulating the transcriptomic profile of multidrug-resistant Klebsiella pneumoniae biofilm formation by antibiotics in combination with zinc sulfate. Annals of Clinical Microbiology and Antimicrobials. 2023 Sep 12;22(1):84. DOI: 10.1186/s12941-023-00634-7 ♦ Farouk F, Zarka MA, Al-Sawahli MM, Hassan A, Mohamed AF, Ibrahim IM, El-Rahman Mohammed FA, Shebl RI. Rosmarinic acid inhibits Rift Valley fever virus: in vitro, computational and analytical studies. Future Virology. 2023 Oct;18(15):1001-19. doi.org/10.2217/fvl-2023-0119 ♦ Farouk F, Shebl RI, Azzazy HM. Antiviral Potential of Microbial Pigments: The Case of Pyocyanin. BIOCHEMISTRY AND CELL BIOLOGY 2023 Dec 1 (Vol. 101, No. 6). 65 AURIGA DR, SUITE 203, OTTAWA, ON K2E 7W6, CANADA: CANADIAN SCIENCE PUBLISHING. dx.doi.org/10.1139/bcb-2023-0300 ♦ Farouk F, Shebl RI. LC-MS/MS determination of pyocyanin-N-acetyl cysteine adduct: application for understanding Pseudomonas aeruginosa virulence factor neutralization. Anal Sci. 2024 Mar 12. 1-15. doi: 10.1007/s44211-024-00531-9. ♦Youssef RA, Sakr MM, Shebl RI, Saad BT, Aboshanab KM. Genomic characterization, in vitro, and preclinical evaluation of two microencapsulated lytic phages VB_ST_E15 and VB_ST_SPNIS2 against clinical multidrug-resistant Salmonella serovars. Ann Clin Microbiol Antimicrob. 2024 Feb 15;23(1):17. https://doi.org/10.1186/s12941-024-00678-3
