Yara Adel Samra

Biography

Experienced associate professor of biochemistry with a demonstrated history of working in the higher education industry. Skilled researcher in Cell Culture, Experimental animal research, Healthcare, and Life Sciences. Strong education professional graduated from Faculty of Pharmacy Mansoura University and worked in Augusta University USA.

Education

- Post-doctoral research fellow in Department of Oral Biology and Diagnostic Sciences, Dental College of Georgia, Augusta University, Augusta, GA 30912, USA. - Ph.D. in pharmaceutical sciences (Biochemistry) Faculty of Pharmacy, Mansoura University, Egypt. Thesis title: " Biochemical study of some compounds in inflammatory pathways in diabetic complications" - Pre-doctoral research fellow in a channel program for completion of the research needed for the Ph.D. dissertation, Department of Ophthalmology and The Culver Vision Discovery Institute, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA. - Master in pharmaceutical sciences (Biochemistry) Faculty of Pharmacy, Mansoura University, Egypt. Thesis title: " Evaluation of Serum Level of Human Epidermal Growth Factor Receptor-2 in Breast Cancer Patients: Correlation with Clinico- Pathological Parameters" - B.Sc. in Pharmaceutical Sciences, Degree excellent, High Honor with grade 94.13% Faculty of Pharmacy, Mansoura University, Egypt.

Department

PUBLICATIONS

1. Mohamed N Amin, Usama Ramadan Abdelmohsen, Yara A Samra. Turkish coffee has an antitumor effect on breast cancer cells in vitro and in vivo. Nutr Metab (Lond). 2024 Sep 13; 21(1): 73. 2. Yara A Samra , Yusra Zaidi, Pragya Rajpurohit , Raju Raghavan , Lun Cai , Ismail Kaddour Djebbar , Amany Tawfik. Warburg Effect as a Novel Mechanism for Homocysteine-Induced Features of Age-Related Macular Degeneration. Int J Mol Sci. (2023) Jan 5;24(2):1071. 3. Nada E Hammouda, Yara A Samra, Ziad Emarah, Amal M El-Gayar. Serum Levels Evaluation of TMSB10 and Endocan in Breast Cancer Patients and In-Vitro Study of Chrysin Effect on These Markers in MCF-7 cell line. Egyptian Journal of Basic and Applied Sciences. (2023), 10, 503-517. 12 4. Randa A Zaghloul, Amr M Abdelghany, Yara A Samra. Rutin and selenium nanoparticles protected against STZ-induced diabetic nephropathy in rats through downregulating Jak-2/Stat3 pathway and upregulating Nrf-2/HO-1 pathway. Eur J Pharmacol. (2022) Oct 15:933:175289. 5. Al Shaima G Abd El Salam, Yara A Samra, Mamdouh M El-Shishtawy. Cinnamaldehyde Relieves Induced Hepatocellular Carcinoma in Rat Model via Targeting Wnt/β-Catenin Pathway. Scientia Pharmaceutica. (2022), 90(2), 22. 6. Mohamed Al-Shabrawey, Ahmed Elmarakby, Yara Samra, Mohamed Moustafa, Stephen W Looney, Krishna Rao Maddipati, Amany Tawfik. Hyperhomocysteinemia dysregulates plasma levels of polyunsaturated fatty acids-derived eicosanoids. Life Res. 2022;5(2):14. 7. Amany M Tawfik, Yara A. Samra, Pragya Rajpurohit, Wagdy Elkalawozgy, Yusra Zaidi. Role of Warburg Effect in Age-Related Macular Degeneration. Investigative Ophthalmology & Visual Science June (2022), Vol.63, 465 – A0002. 8. Fatima A Abdelhameid, Yara A Samra, Mamdouh M El-Shishtawy. Anti-cancer activity of hesperidin against hepatocellular carcinoma-induced in rats through upregulation of RIPK1 expression. Medical Journal of Viral Hepatitis. (2022), Vol.7, 15-20. 9. Omar M Zabad, Yara A Samra, Laila A Eissa. Syringic acid ameliorates experimental diabetic nephropathy in rats through its antiinflammatory, anti-oxidant and anti-fibrotic effects by suppressing Toll like receptor-4 pathway. Metabolism-Clinical and Experimental. 128. (2022). 10. Yara A. Samra, Dina Kira, Pragya Rajpurohit, Riyaz Mohamed, Leah A. Owen, Akbar Shakoor, Ivana Kim, Margaret M. DeAngelis, Nader Sheibani, Mohamed Al-Shabrawey, Amany Tawfik. Implication of N-Methyl-D-aspartate Receptor in Homocysteine-Induced Age- Related Macular Degeneration. https://doi.org/10.3390/ijms22179356 (2021). Int. J. Mol. Sci. 22: 9356. 11. Yara A Samra, Amr M Abdelghany, Randa A Zaghloul. Polydatin gold nanoparticles potentiate antitumor effect of doxorubicin in Ehrlich ascites carcinoma-bearing mice. J Biochem Mol Toxicol. e22869 (2021). 12. Samra YA, Amin MN, Said E. Cardio-protective impact of gabapentin against doxorubicin- induced myocardial toxicity in rats; emphasis on modulation of inflammatory-apoptotic signaling. Int Immunopharmacol. 90:107125 (2021). 13. Tawfik A, Samra YA, Elsherbiny NM, Al-Shabrawey M. Implication of Hyperhomocysteinemia in Blood Retinal Barrier (BRB) Dysfunction. Biomolecules. 10(8):1119 (2020). 14. Ahmed E Khodir , Yara A Samra , Eman Said. A Novel Role of Nifuroxazide in Attenuation of Sepsis-Associated Acute Lung and Myocardial Injuries; Role of TLR4/NLPR3/IL-1β Signaling Interruption. Life Sci. 256:117907 (2020). 15. Elsherbiny NM, Sharma I, Kira D, Alhusban S, Samra YA, Jadeja R, Martin P, Al Shabrawey M, Tawfik A. Homocysteine Induces Inflammation in Retina and Brain. Biomolecules. 10(3):393 (2020). 16. Samra YA, Hamed MF, El-Sheakh AR. Hepatoprotective effect of allicin against acetaminophen-induced liver injury: Role of inflammasome pathway, apoptosis, and liver regeneration. J Biochem Mol Toxicol. e22470 (2020). 17. Manar G. Helal, Yara A. Samra. Irbesartan mitigates acute liver injury, oxidative stress, and apoptosis induced by acetaminophen in mice. J Biochem Mol Toxicol. e22447 (2020). 18. Omar M. Zabad, Yara A. Samra, Laila A.Eissa. P-Coumaric acid alleviates experimental diabetic nephropathy through modulation of Toll like receptor-4 in rats. Life Sci. 238:116965 (2019). 19. Yara A Samra, Mohamed A Katary, Mamdouh M El-Shishtawy, Laila A Essa, Babak Baban, Ahmed A Elmarakby. Cepharanthine improves glycemic status and slows the progression of renal and vascular injury in streptozotocin-induced diabetic rats. FASEB JOURNAL, 32 (1) (2018). 20. Samra YA, Saleh HM, Hussein KA, Elsherbiny NM, Ibrahim AS, Elmasry K, Fulzele S, El- Shishtawy MM, Eissa LA, Al-Shabrawey M, Liou GI. Adenosine Deaminase-2-Induced Hyperpermeability in Human Retinal Vascular Endothelial Cells Is Suppressed by MicroRNA- 146b-3p. Invest Ophthalmol Vis Sci, 58(2): 933-943 (2017). 21. Samra YA, Said HS, Elsherbiny NM, Liou GI, El-Shishtawy MM, Eissa LA. Cepharanthine and Piperine ameliorate diabetic nephropathy in rats: role of NF-κB and NLRP3 inflammasome. Life Sci, 157: 187-199 (2016). 22. Rashad YA, Elkhodary TR, El-Gayar AM, Eissa LA. Evaluation of Serum Levels of HER2, MMP-9, Nitric Oxide, and Total Antioxidant Capacity in Egyptian Breast Cancer Patients: Correlation with Clinico-Pathological Parameters. Sci Pharm, 82(1): 129-145 (2013).